research activity

研究活動

小嶋　勝 (Masaru Kojima)

大阪大学大学院 基礎工学研究科 物質創成専攻
化学工学領域 生物プロセス工学講座 生物材料設計Gr. 准教授
略歴
2019.4 : 大阪大学大学院 基礎工学研究科 物質創成専攻 准教授
2012.3 : 大阪大学大学院 基礎工学研究科 システム創成専攻 助教(～2019.3)．
2008.11 : 名古屋大学大学院 工学研究科 マイクロナノシステム工学専攻 特任助教(～2012.2)．
2007.1 : 名古屋大学大学院 理学研究科 生命理学専攻 研究員 (～2008.10)．
研究分野
研究内容
  • 細胞刺激・操作・計測用マイクロロボットシステムの開発
  • 人工細胞を操作可能なマニピュレーションシステムの開発
  • 高分子材料を応用した機械システムの高機能化
  • マイクロ流体デバイスを応用したものづくり技術の確立
研究業績
  1. Synthesis and application of phenol-grafted rhamnan sulfate for 3D bioprintingRyota Goto, Masahiro Terasawa, Masaru Kojima, Koichi Matsuda, Kaoru Nishiura, Shinji SakaiJournal of Biomaterials Science, Polymer Edition 36(6) 779-795 2024年11月26日  査読有り
  2. Micromixer driven by bubble-induced acoustic microstreaming for multi-ink 3D bioprinting.Mitsuyuki Hidaka, Masaru Kojima, Shinji SakaiLab on a chip 24(19) 4571-4580 2024年9月24日  査読有り
  3. Experimental and numerical approaches for optimizing conjunction area design to enhance switching efficiency in single-nozzle multi-ink bioprinting systemsMitsuyuki Hidaka, Masaru Kojima, Colin Zhang, Yasunori Okano, Shinji SakaiInternational Journal of Bioprinting 4091-4091 2024年8月8日  査読有り
  4. Characterization of Chitosan Hydrogels Obtained through Phenol and Tripolyphosphate Anionic Crosslinking.Mitsuyuki Hidaka, Masaru Kojima, Shinji Sakai, Cédric DelattrePolymers 16(9) 2024年5月2日  査読有り
  5. High-Speed Cell Assembly with Piezo-Driven Two-Finger MicrohandYue Zhao, Yan Deng, Junnan Chen, Masaru Kojima, Qiang Huang, Tatsuo Arai, Xiaoming LiuApplied Sciences (Switzerland) 14(2) 2024年1月  査読有り
  6. Magnetic Microrobots Fabricated by Photopolymerization and AssemblyXiyue Liang, Yue Zhao, Dan Liu, Yan Deng, Tatsuo Arai, Masaru Kojima, Xiaoming LiuCyborg and Bionic Systems 4 2023年  査読有り
  7. Development of non-adherent cell-enclosing domes with enzymatically cross-linked hydrogel shellRyotaro Kazama, Ryuta Sato, Hiroyuki Fujiwara, Yanfei Qu, Masaki Nakahata, Masaru Kojima, Satoshi Fujita, Shinji SakaiBiofabrication 15(1) 2023年1月  査読有り
  8. Noncontact 3-D Orientation Control at Microscale: Hydrodynamic Out-of-Plane Rotation and In-Plane Rotation by Compacted Rotational StageXiaoming Liu, Yuyang Li, Lei Li, Masaru Kojima, Qing Shi, Qiang Huang, Toshio Fukuda, Tatsuo AraiIEEE/ASME Transactions on Mechatronics 27(6) 4807-4818 2022年12月1日  査読有り
  9. A PZT-Driven 6-DOF High-Speed Micromanipulator for Circular Vibration Simulation and Whirling Flow GenerationWeikun Luo, Xiaoming Liu, Xiaoqing Tang, Dan Liu, Masaru Kojima, Qiang Huang, Tatsuo AraiIEEE Robotics and Automation Letters 7(4) 9849-9855 2022年10月1日  査読有り
  10. A Bio-synthetic Hybrid Hydrogel Formed under Physiological Conditions Consisting of Mucin and a Synthetic Polymer Carrying Boronic AcidMasaki Nakahata, Naoki Tominaga, Keishi Saito, Keita Nishiyama, Yuya Tanino, Kiyoshiro Saiki, Masaru Kojima, Shinji SakaiMacromolecular Bioscience 22(6) e2200055 2022年6月  査読有り
  11. Nematode surface functionalization with hydrogel sheaths tailored in situWildan Mubarok, Masaki Nakahata, Masaru Kojima, Shinji SakaiMaterials Today Bio 15 100328-100328 2022年6月  査読有り
  12. Automated Microhand System for Measuring Cell Stiffness By Using Two Plate End-EffectorsMasahiro Kawakami, Masaru Kojima, Yuma Masuda, Yasushi Mae, Takato Horii, Takayuki Nagai, Masaki Nakahata, Shinji Sakai, Tatsuo AraiIEEE Robotics and Automation Letters 7(2) 2385-2390 2022年4月  査読有り
  13. Modulation of Cell-Cycle Progression by Hydrogen Peroxide-Mediated Cross-Linking and Degradation of Cell-Adhesive HydrogelsWildan Mubarok, Kelum Chamara Manoj Lakmal Elvitigala, Masaki Nakahata, Masaru Kojima, Shinji SakaiCells 11(5) 2022年3月1日  査読有り
  14. Development of phenol-grafted polyglucuronic acid and its application to extrusion-based bioprinting inksShinji Sakai, Takashi Kotani, Ryohei Harada, Ryota Goto, Takahiro Morita, Soukaina Bouissil, Pascal Dubessay, Guillaume Pierre, Philippe Michaud, Redouan El Boutachfaiti …Carbohydrate Polymers 277 2022年2月1日  査読有り
  15. Fully-Automated On-Chip Multi-Cell Arraying With Deterministic QuantitiesXiaoming Liu, Xiaoqing Tang, Zhuo Chen, Masaru Kojima, Qiang Huang, Tatsuo AraiIEEE Transactions on Automation Science and Engineering 19(2) 724-734 2022年  査読有り
  16. Object segmentation in cluttered environment based on gaze tracing and gaze blinkingPhotchara Ratsamee, Yasushi Mae, Kazuto Kamiyama, Mitsuhiro Horade, Masaru Kojima, Tatsuo AraiROBOMECH Journal 8(1) 2021年12月  査読有り
  17. A tetrahedral DNA nanorobot with conformational change in response to molecular triggerFengyu Liu, Xiaoming Liu, Qing Shi, Christopher Maffeo, Masaru Kojima, Lixin Dong, Aleksei Aksimentiev, Qiang Huang, Toshio Fukuda, Tatsuo AraiNanoscale 13(37) 15552-15559 2021年10月7日  査読有り
  18. Automated Cell Mechanical Characterization by On-Chip Sequential Squeezing: From Static to DynamicPengyun Li, Xiaoming Liu, Masaru Kojima, Qiang Huang, Tatsuo AraiLangmuir 37(27) 8083-8094 2021年7月13日  査読有り
  19. Visible light-curable chitosan ink for extrusion-based and vat polymerization-based 3d bioprintingsMitsuyuki Hidaka, Masaru Kojima, Masaki Nakahata, Shinji SakaiPolymers 13(9) 2021年5月1日  査読有り
  20. Magnetic driven two-finger micro-hand with soft magnetic end-effector for force-controlled stable manipulation in microscaleDan Liu, Xiaoming Liu, Pengyun Li, Xiaoqing Tang, Masaru Kojima, Qiang Huang, Tatsuo AraiMicromachines 12(4) 2021年4月  査読有り
  21. In-Situ Bonding of Multi-Layer Microfluidic Devices Assisted by an Automated Alignment SystemPengyun Li, Xiaoming Liu, Dan Liu, Xiaoqing Tang, Masaru Kojima, Qiang Huang, Tatsuo AraiIEEE Robotics and Automation Letters 6(2) 2611-2617 2021年4月  査読有り
  22. Efficient Single-Cell Mechanical Measurement by Integrating a Cell Arraying Microfluidic Device with Magnetic TweezerXiaoqing Tang, Xiaoming Liu, Pengyun Li, Dan Liu, Masaru Kojima, Qiang Huang, Tatsuo AraiIEEE Robotics and Automation Letters 6(2) 2978-2984 2021年4月  査読有り
  23. A wearable navigation device for visually impaired people based on the real-time semantic visual slam systemZhuo Chen, Xiaoming Liu, Masaru Kojima, Qiang Huang, Tatsuo AraiSensors 21(4) 1-14 2021年2月2日  査読有り
  24. All-Purpose Magnetic Micromanipulation System with Two Modes: Chopstick-Like Two-Finger Microhand and Hydrodynamic TweezerDan Liu, Xiaoming Liu, Pengyun Li, Xiaoqing Tang, Masaru Kojima, Qiang Huang, Tatsuo AraiIEEE/ASME Transactions on Mechatronics 2021年  査読有り
  25. On-Chip Cell-Cell Interaction Monitoring at Single-Cell Level by Efficient Immobilization of Multiple Cells in Adjustable QuantitiesXiaoqing Tang, Xiaoming Liu, Pengyun Li, Fengyu Liu, Masaru Kojima, Qiang Huang, Tatsuo AraiAnalytical Chemistry 92(17) 11607-11616 2020年9月1日  査読有り
  26. High-speed manipulation of microobjects using an automated two-fingered microhand for 3D microassemblyEunhye Kim, Masaru Kojima, Yasushi Mae, Tatsuo AraiMicromachines 11(5) 2020年5月1日  査読有り
  27. Extrusion-based bioprinting through glucose-mediated enzymatic hydrogelationEnkhtuul Gantumur, Masaki Nakahata, Masaru Kojima, Shinji SakaiInternational Journal of Bioprinting 6(1) 43-52 2020年  査読有り
  28. Multifunctional Noncontact Micromanipulation Using Whirling Flow Generated by Vibrating a Single Piezo ActuatorXiaoming Liu, Qing Shi, Yuqing Lin, Masaru Kojima, Yasushi Mae, Toshio Fukuda, Qiang Huang, Tatsuo AraiSmall 15(5) 2019年2月1日  査読有り
  29. Energy-efficient narrow wall climbing of six-legged robotKenichi Ohara, Takeshi Toda, Kazuto Kamiyama, Masaru Kojima, Mitsuhiro Horade, Yasushi Mae, Tatsuo Arai, Tatsuo AraiROBOMECH Journal 5 2018年12月  査読有り
  30. Vortex-Driven Rotation for Three-Dimensional Imaging Under MicroscopyXiaoming Liu, Qing Shi, Yuqing Lin, Masaru Kojima, Yasushi Mae, Qiang Huang, Toshio Fukuda, Tatsuo AraiIEEE Transactions on Nanotechnology 17(4) 688-691 2018年7月  査読有り
  31. Hydrodynamic tweezers: Trapping and transportation in microscale using vortex induced by oscillation of a single piezoelectric actuatorXiaoming Liu, Qing Shi, Yuqing Lin, Masaru Kojima, Yasushi Mae, Qiang Huang, Toshio Fukuda, Tatsuo AraiSensors (Switzerland) 18(7) 2018年7月1日  査読有り
  32. High-Speed Active Release End-Effector Motions for Precise Positioning of Adhered Micro-ObjectsEunhye Kim, Masaru Kojima, Kazuto Kamiyama, Mitsuhiro Horade, Yasushi Mae, Tatsuo AraiWorld Journal of Engineering and Technology 6(1) 81-103 2018年2月  査読有り
  33. Real-time 3D measurement system for micro-manipulationKenichi Ohara, Shota Takagi, Masaru Kojima, Mitsuhiro Horade, Kazuto Kamiyama, Yasushi Mae, Tatsuo AraiInternational Journal of Mechatronics and Automation 6(4) 183-189 2018年1月  査読有り
  34. Analysis of rotational flow generated by circular motion of an end effector for 3D micromanipulationEunhye Kim, Masaru Kojima, Liu Xiaoming, Takayuki Hattori, Kazuto Kamiyama, Yasushi Mae, Tatsuo AraiROBOMECH Journal 4(1) 2017年12月1日  査読有り
  35. Microchip device with parallel operation for bacterial chemotactic analysisMasaru Kojima, Zhiqin Wang, Masahiro Nakajima, Tatsuo Arai, Toshio FukudaSENSORS AND ACTUATORS B-CHEMICAL 245 695-701 2017年6月  査読有り
  36. Development of a Novel 2-Dimensional Micro-Heater Array Device with Regional Selective HeatingMitsuhiro Horade, Masaru Kojima, Kazuto Kamiyama, Yasushi Mae, Tatsuo AraiMechanical Engineering Research 6(1) 66-74 2016年4月  査読有り
  37. Releasing of micro-objects based on local stream generation by high speed motion of end-effectorEunhye Kim, Masaru Kojima, Kazuto Kamiyama, Mitsuhiro Horade, Yasushi Mae, Tatsuo AraiInternational Journal of Mechatronics and Automation 5(4) 171-179 2016年  査読有り
  38. A 3D culture model study monitoring differentiation of dental epithelial cells into ameloblast-like cellsMayu Tadaki, Takahisa Anada, Yukari Shiwaku, Takashi Nakamura, Masanori Nakamura, Masaru Kojima, Tatsuo Arai, Satoshi Fukumoto, Osamu SuzukiRSC ADVANCES 6(67) 62109-62118 2016年  査読有り
  39. Bacterial sheet-powered rotation of a micro-objectMasaru Kojima, Tatsuya Miyamoto, Masahiro Nakajima, Michio Homma, Tatsuo Arai, Toshio FukudaSENSORS AND ACTUATORS B-CHEMICAL 222 1220-1225 2016年1月  査読有り
  40. Generation of rotational flow for formation of spheroids by using microfluidic and dielectrophoretic hybrid deviceMasaru Kojima, Mitsuhiro Horade, Hirochika Takai, Kenichi Ohara, Tamio Tanikawa, Kazuto Kamiyama, Yasushi Mae, Tatsuo AraiInternational Journal of Mechatronics and Automation 5(4) 180-189 2016年  査読有り
  41. A new close-loop control method for an inspection robot equipped with electropermanent-magnetsPakpoom Kriengkomol, Kazuto Kamiyama, Masaru Kojima, Mitsuhiro Horade, Yasushi Mae, Tatsuo AraiJournal of Robotics and Mechatronics 28(2) 185-193 2016年  査読有り
  42. Social interactive robot navigation based on human intention analysis from face orientation and human path predictionPhotchara Ratsamee, Yasushi Mae, Kazuto Kamiyama, Mitsuhiro Horade, Masaru Kojima, Tatsuo AraiROBOMECH Journal 2(1) 2015年12月1日  査読有り
  43. Development of an optimum end-effector with a nano-scale uneven surface for non-adhesion cell manipulation using a micro-manipulatorM. Horade, M. Kojima, K. Kamiyama, T. Kurata, Y. Mae, T. AraiJOURNAL OF MICROMECHANICS AND MICROENGINEERING 25(11) 2015年11月  査読有り
  44. Keyframe Selection Framework Based on Visual and Excitement Features for Lifelog Image SequencesPhotchara Ratsamee, Yasushi Mae, Amornched Jinda-apiraksa, Mitsuhiro Horade, Kazuto Kamiyama, Masaru Kojima, Tatsuo AraiINTERNATIONAL JOURNAL OF SOCIAL ROBOTICS 7(5) 859-874 2015年11月  査読有り
  45. Piezo-actuated parallel mechanism for biological cell release at high speedEbubekir Avci, Takayuki Hattori, Kazuto Kamiyama, Masaru Kojima, Mitsuhiro Horade, Yasushi Mae, Tatsuo AraiBIOMEDICAL MICRODEVICES 17(5) 2015年10月  査読有り
  46. High-Speed Automated Manipulation of Microobjects Using a Two-Fingered MicrohandEbubekir Avci, Kenichi Ohara, Chanh-Nghiem Nguyen, Chayooth Theeravithayangkura, Masaru Kojima, Tamio Tanikawa, Yasushi Mae, Tatsuo AraiIEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS 62(2) 1070-1079 2015年2月  査読有り
  47. Brain signal-based safety measure activation for robotic systemsChristian I. Penaloza, Yasushi Mae, Masaru Kojima, Tatsuo AraiADVANCED ROBOTICS 29(19) 1234-1242 2015年  査読有り
  48. Flexible microscaffold facilitating the in vitro construction of different cellular constructsPuwanan Chumtong, Masaru Kojima, Mitsuhiro Horade, Kenichi Ohara, Kazuto Kamiyama, Yasushi Mae, Yoshikatsu Akiyama, Masayuki Yamato, Tatsuo AraiROBOMECH Journal 1(1) 2014年12月1日  査読有り
  49. Brain Machine Interface System Automation Considering User Preferences and Error Perception FeedbackChristian I. Penaloza, Yasushi Mae, Francisco F. Cuellar, Masaru Kojima, Tatsuo AraiIEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING 11(4) 1275-1281 2014年10月  査読有り
  50. Construction and evaluation of bacteria-driven liposomeMasaru Kojima, Zhenhai Zhang, Masahiro Nakajima, Katsutoshi Ooe, Toshio FukudaSENSORS AND ACTUATORS B-CHEMICAL 183 395-400 2013年7月  査読有り
  51. 感熱応答性ゲルによるマイクロオブジェクト把持プローブの作製および応用竹内 大, 中島 正博, 小嶋 勝, 福田 敏男日本ロボット学会誌 31(3) 275-282 2013年4月15日  査読有り
  52. Handling of micro objects using phase transition of thermoresponsive polymerMasaru Takeuchi, Masahiro Nakajima, Masaru Kojima, Toshio FukudaJournal of Micro-Nano Mechatronics 8(2) 53-64 2013年  査読有り
  53. Design and fabrication of changeable cell culture moldPuwanan Chumtong, Masaru Kojima, Kenichi Ohara, Yasushi Mae, Mitsuhiro Horade, Yoshikatsu Akiyama, Masayuki Yamato, Tatsuo AraiJournal of Robotics and Mechatronics 25(4) 657-664 2013年  査読有り
  54. Automated construction system for 3D lattice structure based on alginate gel fiber containing living cellsKenichi Ohara, Masaru Kojima, Akira Fukushima, Shun Onozaki, Mitsuhiro Horade, Masumi Yamada, Minoru Seki, Yasushi Mae, Tatsuo AraiJournal of Robotics and Mechatronics 25(4) 665-672 2013年  査読有り
  55. High efficiency motility of bacteria-driven liposome with raft domain binding methodMasaru Kojima, Zhenhai Zhang, Masahiro Nakajima, Toshio FukudaBIOMEDICAL MICRODEVICES 14(6) 1027-1032 2012年12月  査読有り
  56. Microchip device for measurement of body volume of C. elegans as bioindicator applicationJaehoon Jung, Masahiro Nakajima, Masaru Kojima, Katsutoshi Ooe, Toshio FukudaJournal of Micro-Nano Mechatronics 7(1-3) 3-11 2012年12月  査読有り
  57. Nanofork for Single Cells Adhesion Measurement via ESEM-Nanomanipulator SystemMohd Ridzuan Ahmad, Masahiro Nakajima, Masaru Kojima, Seiji Kojima, Michio Homma, Toshio FukudaIEEE TRANSACTIONS ON NANOBIOSCIENCE 11(1) 70-78 2012年3月  査読有り
  58. Instantaneous and Quantitative Single Cells Viability Determination Using Dual Nanoprobe Inside ESEMMohd Ridzuan Ahmad, Masahiro Nakajima, Masaru Kojima, Seiji Kojima, Michio Homma, Toshio FukudaIEEE TRANSACTIONS ON NANOTECHNOLOGY 11(2) 298-306 2012年3月  査読有り
  59. Single cell adhesion force measurement for cell viability identification using an AFM cantilever-based micro putterYajing Shen, Masahiro Nakajima, Seiji Kojima, Michio Homma, Masaru Kojima, Toshio FukudaMEASUREMENT SCIENCE AND TECHNOLOGY 22(11) 2011年11月  査読有り
  60. ナノ・マイクロデュアルピペットを用いた局所環境制御システムによるべん毛モータ駆動力の制御野川 晃佑, 小嶋 勝, 中島 正博, 本間 道夫, 福田 敏男日本ロボット学会誌 29(5) 463-469 2011年6月15日  査読有り
  61. Phase behavior of crowded like-charged mixed polyelectrolytes in a cell-sized sphereMakiko Negishi, Masatoshi Ichikawa, Masahiro Nakajima, Masaru Kojima, Toshio Fukuda, Kenichi YoshikawaPHYSICAL REVIEW E 83(6) 2011年6月  査読有り
  62. Conversion of mono-polar to peritrichous flagellation in Vibrio alginolyticusMasaru Kojima, Noriko Nishioka, Akiko Kusumoto, Jin Yagasaki, Toshio Fukuda, Michio HommaMICROBIOLOGY AND IMMUNOLOGY 55(2) 76-83 2011年2月  査読有り
  63. Quantitative Evaluation of Injected Molecules into Phospholipid-Coated Microdroplets for In situ Biological Reactions.Masahiro Nakajima, Yuta Matsuno, Masaru Kojima, Yohko Takiguchi, Kingo Takiguchi, Kousuke Nogawa, Michio Homma, Toshio FukudaJ. Robotics and Mechatronics 22(5) 651-658 2010年10月  査読有り
  64. Nanoliters Discharge/Suction by Thermoresponsive Polymer Actuated Probe and Applied for Single Cell Manipulation.Masaru Takeuchi, Masahiro Nakajima, Masaru Kojima, Toshio FukudaJ. Robotics and Mechatronics 22(5) 644-650 2010年10月  査読有り
  65. 脂質-重膜ドロップレット内へのマイクロ・ナノピペットによる極微少量噴出とその定量評価(機械力学,計測,自動制御)中島 正博, 松野 雄多, 瀧口 陽子, 野川 晃佑, 瀧口 金吾, 小嶋 勝, 本間 道夫, 福田 敏男日本機械学会論文集 C編 76(766) 1547-1552 2010年  査読有り
  66. Interaction between Na+ Ion and Carboxylates of the PomA-PomB Stator Unit Studied by ATR-FTIR SpectroscopyYuki Sudo, Yuya Kitade, Yuji Furutani, Masaru Kojima, Seiji Kojima, Michio Homma, Hideki KandoriBIOCHEMISTRY 48(49) 11699-11705 2009年12月  査読有り
  67. Rotational Speed Control of Na+-Driven Flagellar Motor by Dual PipettesKousuke Nogawa, Masaru Kojima, Masahiro Nakajima, Seiji Kojima, Michio Homma, Toshio FukudaIEEE TRANSACTIONS ON NANOBIOSCIENCE 8(4) 341-348 2009年12月  査読有り
  68. The bidirectional polar and unidirectional lateral flagellar motors of Vibrio alginolyticus are controlled by a single CheY speciesMasaru Kojima, Rumi Kubo, Toshiharu Yakushi, Michio Homma, Ikuro KawagishiMOLECULAR MICROBIOLOGY 64(1) 57-67 2007年4月  査読有り
  69. Isolation of Vibrio alginolyticus sodium-driven flagellar motor complex composed of PomA and PomB solubilized by sucrose monocaprateT Yakushi, M Kojima, K HommaMICROBIOLOGY-SGM 150 911-920 2004年4月  査読有り
  70. Multimeric structure of the PomA/PomB channel complex in the Na+-driven flagellar motor of Vibrio alginolyticusT Yorimitsu, M Kojima, T Yakushi, M HommaJOURNAL OF BIOCHEMISTRY 135(1) 43-51 2004年1月  査読有り
  71. MotX and MotY, specific components of the sodium-driven flagellar motor, colocalize to the outer membrane in Vibrio alginolyticusMayuko Okabe, Toshiharu Yakushi, Masaru Kojima, Michio HommaMolecular Microbiology 46(1) 125-134 2002年  査読有り

JKA 機械振興補助事業 研究補助 高精度バイオ3Dプリンティングを実現するマイクロ流体ノズルの開発補助事業 (研究期間 2023年4月 – 2025年3月)の内容とそれ関わる業績

内容

バイオ3Dプリンティングの高度化を目指し、解像度を上げたより高精度な造形や、直線だけでは表現できない複雑な形状の造形を実現する、マイクロ流路を組み込んだマイクロ流体ノズルを開発に取り組みました。

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